Postinfectious Cough: Prevalence
When a patient complains of cough that has been present following symptoms of an acute respiratory infection for at least 3 weeks, but not more than 8 weeks, consider a diagnosis of postinfectious cough. Quality of evidence, expert opinion; net benefit, intermediate; strength of recommendation, E/B
In patients with subacute postinfectious cough, because there are multiple pathogenetic factors that may contribute to the cause of cough (including postviral airway inflammation with its attendant complications such as bronchial hyperresponsiveness, mucus hypersecretion and impaired mucociliary clearance, upper airway cough syndrome [UACS], asthma, and gastroesophageal reflux disease), judge which factors are most likely provoking cough before considering therapy. Quality of evidence, expert opinion; net benefit, intermediate; strength of recommendation, E/B buy birth control
In adults, postinfectious cough has been reported with a variable frequency. In retrospective stud-ies’2’’ of unselected patients with a history of upper respiratory tract infection, the frequency has ranged from 11 to 25%. During outbreaks of obvious infection with M pneumoniae and Bordetella pertussis, the frequency of postinfectious cough increases to 25 to 50% in selected series. In prospective studies of unselected patients, many of whom had a history of upper respiratory tract infection, postinfectious cough was not diagnosed. The explanation for this low frequency in the latter studies is likely related to differences in the study populations reported and to the fact that most patients in these series had experienced the cough for many months or years. In children, the specific infection causing the postinfectious cough in most cases remains unidentified. Respiratory viruses (particularly respiratory syncytial virus, influenza, parainfluenza, and adenovirus), M pneumoniae, Chlamydophila pneumoniae strain TWAR, Moraxella catarrhalis, and B pertussis have all been implicated. In the general population, there is an average of 2.2 viral respiratory infections per person per year, but in children this number is considerably higher.
Category: Respiratory Symptoms
Tags: Bordetella pertussis, pertussis infection, postinfectious cough, postviral cough