Gallbladder polyps: CLINICAL SIGNIFICANCE OF GALLBLADDER POLYPS Part 2

CLINICAL SIGNIFICANCE OF GALLBLADDER POLYPSFor example, in a study of 74 patients with resected gallbladders and small polyps (smaller than 2.0 cm in diameter), cholesterol polyps were found in 44 cases (59%), adenomas in five cases (7%), cancers in six cases (8%), and other conditions, including hyperplastic polyps and adeno-myomatosis, in 19 cases (26%). Whereas the mean diameters of cholesterol polyps and adenomas were 3.7 mm and 6.0 mm, respectively, the mean diameter of the carcinomas was 10.8 mm. Almost all (97%) of the cholesterol polyps were less than 10 mm in diameter, and 82% were smaller than 5 mm. On the contrary, only 6% of the adenomas or carcinomas were less than 5 mm in diameter. Importantly, the number of lesions in each group also differed. Whereas approximately 80% of neoplastic lesions were solitary (mean number of adenomas 1.40; mean number of carcinomas 1.16), cholesterol polyps were more commonly multiple (50%; mean 3.09). All of the cases of four or more polyps in this series were cholesterol polyps. Over 50% of polyps exceeding 10 mm were neoplastic. In those with fewer than three polyps (5 to 10 mm in diameter), the frequency of neoplasm was 37%. Other investigators have corroborated the importance of polyp number as a discriminating feature. For example, in an analysis of 172 patients with histologically confirmed PLG, Yang and colleagues reported that all of the 13 malignant PLG were solitary, whereas none of the 86 patients with multiple PLG harboured a malignancy. Your drugs could cost you less – yasmin birth to start the treatment soon.

This entry was posted in Gallbladder and tagged allbladder neoplasms, Gallbladder, Gallbladder polyps, Gallstones, Surgery, Ultrasonography.