Escherichia coli O157:H7, other verotoxin-producing E coli and the hemolytic uremic syndrome in childhood: part 7

childhood: part 7

HOW IS HUS TREATED?
If hus is suspected, the child should be referred to a centre with a specialist skilled in the management of these patients. Although large bo I uses of oral or intravenous flu i ds are usually indicated in dehydrated children with oliguria, the same therapy for oliguric children with hus can be disastrous because of the potential for overhydration, hyponatremia and seizures.Current treatment for the child with hus consists of careful fluid administration during periods of oliguria or anuria, judicious blood product replacement, treatment of electrolyte disturbances, control of seizures and hypertension and, when necessary, dialysis. Early specialized medical care has been responsible in part for the reduction in hus mortality from 100% in 1955 to 2.6% among Canadian children in 1986-88. hus remains a serious illness, with up to 50% of affected children in some centres receiving either peritoneal dialysis or hemodialysis and with a mean length of dialysis of 14 days. Several stud I es have demonstrated long term morbidity following hus, including progressive reductions in renal function in some children after discharge from hospital and, less commonly, permanent central nervous system dysfunction ranging from mental retardation and hemiparesis to learning disabilities. Buy cheap drugs online fast – buy asthma inhaler for you to enjoy a reliable pharmacy.

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