Escherichia coli O157:H7, other verotoxin-producing E coli and the hemolytic uremic syndrome in childhood: part 4

HOW ARE VTEC INFECTION AND HUS RECOGNIZED CLINICALLY?
Gastro tntestinal infection with E coli O157:H7 most commonly begins with a crampy, watery diarrhea after an incubation period of three to four days (range one to 10 days). Infection may also progress to bloody diarrhea with stools containing amounts of blood ranging from streaks to grossly visible blood. The proportion of patients who go on to develop bloody diarrhea is unknown because those with non-bloody diarrhea are less likely to have stool cultures pert formed.In clinical series, bloody stools are observed in over 75% of patients and usually are evident one to three days after the onset of illness. Half the patients also have vomiting, but only about one-third develop fever. In the majority of patients, symptoms usually resolve after a week. More severe manifestations of this illness include intussusception, rectal prolapse, hemo tytic anemia and hus or thrombotic thrombocytopenic purpura.

Hus typically appears abruptly five to nine days after the onset of gastro t ntestinal symptoms but can occur as early as one to two days after diarrhea begins. hus is recognized by the rapid development of hemolytic anemia, thrombocytopenia and evidence of acute renal injury, in conjunction with variable degrees of central nervous system dystunction (including lethargy, seizures or coma). It is now clear that hus can also occur in a subclinical form, in which renal injury escapes recognition because the child continues to produce urine, and in an incomplete form, in which pati ents have hemolytic anemia or thrombocytopenia without evidence of acute renal inj ury. Your drugs could be so cheap – get actos diabetes at trusted foreign online pharmacy.

This entry was posted in Escherichia coli O157:H7 and tagged Escherichia coli, GASTROENTERITIS, O157:H7 INFECTION.