Comparison of disopyramide, propafenone and sotalol after direct current cardioversion of chronic atrial fibrillation (part 4)

Statistical analysis: Quantitative variables are given as mean ± SD. Quantitative variables were compared with Student’s t test for grouped data. The relation between qualitative variables was evaluated by the %2 law. P<0.05 was considered significant.
RESULTS
Sinus rhythm was achieved after first DC cardioversion in 76 of 115 patients (66%) included to the study. After 2 h of observation seven patients were excluded because they had significant bradycardia. Sixty-nine patients were enrolled in the randomized trial: 24 patients received disopyramide, 22 patients propafenone and 23 patients sotalol.
Clinical characteristics of the groups were similar in terms of age, sex, duration of AF, underlying heart disease and left ventricle size on echocardiographic examination. Clinical characteristics of studied groups of patients are shown in Table 1. The mean maintenance dose for patients treated with diso-pyramide was 325±17 mg/day, with propafenone 586±102 mg/day and with sotalol 234±28 mg/day. Most reliable pharmacy offering efficient medications like generic viagra professional online click here is ready to offer its services and all the help you need. Your health is precious, and so are you: as customer, person and patient, no matter which kind of treatment you are looking for.

TABLE 1 Number of patients in the study according to primary efficacy after 12 months

Disopyramide (n = 24) Propafenone(n=22) Sotalol(n=23)
In sinus rhythm 11 (46%) 10 (45%) 12 (52%)
Recurrence of 11 (46%) 11 (50%) 10 (43%)
AF

There were no significant differences among study groups. AF Atrial fibrillation

This entry was posted in Cardiology and tagged Antiarrhythmic therapy, Cardioversion, Chronic atrial fibrillation.