Category Archives: Sarcoidosis

Relationship Between Presentation of Sarcoidosis and T Lymphocyte Profile: Conclusion

Lymphocytic alveolitis is an early event in the evolution of pulmonary involvement in sarcoidosis. This inflammatory response precedes granuloma formation in the lung and may be latently present without clinical or physiologic impairment, while remaining undetected by radiologic investigation. It … Continue reading

Relationship Between Presentation of Sarcoidosis and T Lymphocyte Profile: Discussion

The results presented in this study confirm previous observations of signs of a T lymphocyte alveolitis and the influence of smoking on T lymphocyte subsets in patients with sarcoidosis. Most remarkably, we demonstrated that the BAL fluid T lymphocyte profiles … Continue reading

Relationship Between Presentation of Sarcoidosis and T Lymphocyte Profile: Results

The mean values ± SEM of the immunologic marker analysis of the cells in BAL fluid and peripheral blood (PB) samples of the groups studied are summarized in Table 2. In general, the cellular components of BAL fluid samples obtained … Continue reading

Relationship Between Presentation of Sarcoidosis and T Lymphocyte Profile: Materials and Methods

Patients and Control Subjects Bronchoalveolar lavage was performed in 100 patients with histologically proven sarcoidosis and 14 control subjects. The characteristics of the patients and control subjects are described in Table 1. The patients were divided into three groups based … Continue reading

Relationship Between Presentation of Sarcoidosis and T Lymphocyte Profile

Sarcoidosis is a disorder of unknown origin, characterized by the formation of noncaseating epithelioid cell granulomas, probably antigen driven, most frequently occurring in the lungs. In addition to granuloma formation, there is often an extensive vascular disease as seen by … Continue reading