Category Archives: Respiratory Symptoms - Part 13

Femoral Vein Pulmonary Artery Catheterization in the Intensive Care Unit: Methods

Since its introduction into clinical use, the pulmonary artery catheter has helped physicians to understand and manage the rapid and potentially disastrous changes in cardiopulmonary physiology that may occur in the critically ill. As with any new instrument, the increased … Continue reading

Airway Response to a Bronchodilator in Healthy Parents of Infants With Bronchiolitis: Discussion

Our study shows that healthy parents of infants with bronchiolitis have a high prevalence of bronchial hyperresponsiveness as defined by the bronchodilator response. The number of parents (24.2 percent) with a positive bronchodilator response suggests that there may be a … Continue reading

Airway Response to a Bronchodilator in Healthy Parents of Infants With Bronchiolitis: Results

Main characteristics of the investigated subjects are reported in Table 1. There was no significant difference for anthropometric parameters nor for smoking habit between the two groups. As stated in the Materials and Methods section, both groups had normal mean … Continue reading

Airway Response to a Bronchodilator in Healthy Parents of Infants With Bronchiolitis: Materials and Methods

From January through March 1992, we have studied 132 adults (66 males and 66 females) in good past and present health at least 4 weeks after any upper respiratory tract infection. Informed consent was obtained before participation in the study. … Continue reading

Airway Response to a Bronchodilator in Healthy Parents of Infants With Bronchiolitis

Bronchiolitis is a viral disease of the lower respiratory tract resulting from inflammatory obstruction of the small airways. It occurs under 2 years of age and is characterized by the acute onset of serous nasal discharge, wheezing, cough, and dyspnea … Continue reading

Amplitude-modulated Ventilation: Conclusions

We have modeled the pressure response to a deep lung inflation as that caused by an impulse change in volume, and have defined the compliance as V(t)/P(t) following the impulse input. This is equivalent to the time derivative of the … Continue reading

Amplitude-modulated Ventilation: Discussion

The first inequality is a formal quantitative statement of the notion that a region of deformed parenchyma subject to external shear will maintain its patency as long as it maintains its ability to resist further shear. The second inequality states … Continue reading

Amplitude-modulated Ventilation: Results

The dynamic relaxation properties of surfactant samples collected from control and injured animals were compared by measuring film surface tension as a function of time following a step change in bubble volume of 50 percent. Surface tension profiles as a … Continue reading

Amplitude-modulated Ventilation: Methods

We studied this hypothesis in an animal model of ALI. Male Hartley guinea pigs, weight 550 to 600 g, were treated with inhaled solubilized endotoxin (time = 0) followed by continuous intravenous infusion (time = 12 to 18 h) while … Continue reading

Amplitude-modulated Ventilation

The histopathology of acute lung injury (ALI) is characterized by alveolar septal thickening, hyaline membrane formation, and neutrophil infiltration. The physiologic consequence of these abnormalities is hypoxemia due primarily to alveolar instability and collapse with an increase in the number … Continue reading

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