Category Archives: Respiratory Symptoms

Chronic Thromboembolic and Pulmonary Arterial Hypertension Share Acute Vasoreactivity Properties: Follow-up of Patients After This Initial Hemodynamic Evaluation

This concept is supported by data indicating that the mechanisms leading to PH in patients who have experienced repeated pulmonary thromboembolic events are not only mechanistic (ie, nonrecanalized thrombotic vessel occlusion), but possibly also are related to vascular remodeling that … Continue reading

Chronic Thromboembolic and Pulmonary Arterial Hypertension Share Acute Vasoreactivity Properties: Follow-up of Patients After This Initial Hemodynamic Evaluation

After this diagnostic hemodynamic baseline examination, patients with PAH were treated with regular iILO (n = 18), bosentan (n = 16), and/or sildenafil (n = 2). The initial treatment of patients with CTEPH was with iILO (n = 20) and/or … Continue reading

Chronic Thromboembolic and Pulmonary Arterial Hypertension Share Acute Vasoreactivity Properties: Patient Characteristics

A total of 57 patients, 35 with PAH and 22 with CTEPH, were included in the study. Patient characteristics are presented in Table 1. Patients with CTEPH were on average older than those with PAH, and had lower CI, Sa02, … Continue reading

Chronic Thromboembolic and Pulmonary Arterial Hypertension Share Acute Vasoreactivity Properties: Testing Protocol

Pulmonary and systemic arterial pressures and the right atrial pressure (RAP) were continuously recorded, and the pulmonary artery occlusion pressure (PAOP) was recorded intermittently. The cardiac output (CO) was assessed by thermodilution (Cardiac Output Computer; Baxter/Edwards). The cardiac index (CI) … Continue reading

Chronic Thromboembolic and Pulmonary Arterial Hypertension Share Acute Vasoreactivity Properties: Patient Population

Thirty-five patients with PAH and 22 patients with CTEPH were included in the study after obtaining written informed consent. The study was approved by the local ethics committee. PAH was diagnosed as idiopathic (n = 25) if the evaluation performed … Continue reading

Chronic Thromboembolic and Pulmonary Arterial Hypertension Share Acute Vasoreactivity Properties

Structural and functional changes in the vascular wall and thrombus formation are the main factors responsible for increased pulmonary vascular resistance (PVR) in patients with pulmonary hypertension (PH). The contribution of each of these factors is thought to be different … Continue reading

Sleep in Critically III Chemically Paralyzed Patients Requiring Mechanical Ventilation: Recommendation

Gender is shown to have little objective effect on polysomnography sleep architecture or sleep regulation. Women (age > 50 years) may have slightly better SWS preservation than men. Power spectral analysis has shown a small increase in delta, theta, and … Continue reading

Sleep in Critically III Chemically Paralyzed Patients Requiring Mechanical Ventilation: Summary

Increased low amplitude delta waves may be related to septic encephalopathy. In the study by Cooper et al, septic encephalopathy was thought less likely due to negative blood culture results. However, in the study by Gabor et al, five of … Continue reading

Sleep in Critically III Chemically Paralyzed Patients Requiring Mechanical Ventilation: Conclusion

Electrolyte imbalance, liver failure, renal failure, anoxic-ischemic brain injury, drugs, and sepsis may all contribute to encephalopathy. None of our patients had neurologic signs that may be associated with encephalopathy, such as tremor, myoclonus, or asterixis. Four patients had an … Continue reading

Sleep in Critically III Chemically Paralyzed Patients Requiring Mechanical Ventilation: Causes

In their study, 6 of 11 patients had congestive heart failure likely contributing to the central apneas associated with PS ventilation. Our patient population consisted mainly of individuals with COPD and pneumonia leading to respiratory failure. Although none of our … Continue reading

Pages: 1 2 3 4 5 6 7 8 9 10 ... 12 13 14 Next