Category Archives: COPD - Part 2

Skin Manifestations of Inhaled Corticosteroids in COPD Patients: Easy Bruising

The adverse skin conditions that are well-recognized to result from or be associated with systemic corticosteroid use are listed in Table 2. Among these, rash, easy bruising, and slow healing differ between the groups, suggesting some systemic absorption. The reports … Continue reading

Skin Manifestations of Inhaled Corticosteroids in COPD Patients: Results

Differences in baseline characteristics between the ICS and placebo groups were assessed using t tests for continuous variables and x2 tests for categoric variables. Differences in the rates of new or worsening skin conditions were compared using the Wilcoxon rank-sum … Continue reading

Skin Manifestations of Inhaled Corticosteroids in COPD Patients: Assessment of Skin Changes

Every 6 months, beginning at the 18-month or 24-month visit, participants were administered a structured questionnaire in which they were asked whether, since their last clinic visit, they had experienced any skin rashes (and the percentage of time any skin … Continue reading

Skin Manifestations of Inhaled Corticosteroids in COPD Patients: Materials and Methods

Study Sample LHS II recruited 1,116 participants at 10 clinical centers in the United States and Canada. These were individuals who participated in LHS I (1,018 persons) or were screened for LHS I (98 persons), and were still smoking or … Continue reading

Skin Manifestations of Inhaled Corticosteroids in COPD Patients: LHS

A few randomized, placebo-controlled clinical trials in persons with COPD have systematically evaluated the frequency of bruising as a complication of moderate-to-high doses of ICSs.-’ However, these relied mainly on nondirected complaints regarding adverse events or direct observation of large … Continue reading

Skin Manifestations of Inhaled Corticosteroids in COPD Patients

Inhaled corticosteroids (ICSs) are generally recommended as first-line controller agents for the management of persistent asthma and also have been investigated in several large-scale randomized, controlled clinical trials for their possible efficacy in stable COPD patients, with partially favorable results … Continue reading

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