Category Archives: Cardiology - Part 2

Comparison of disopyramide, propafenone and sotalol after direct current cardioversion of chronic atrial fibrillation (part 6)

In 24 h Holter ECG monitoring after one week and six months of antiarrhythmic therapy a significant difference was observed in minimal heart rate. The lowest heart rate was observed in the sotalol group (Tables 3,4). Adverse side effects: Several … Continue reading

Comparison of disopyramide, propafenone and sotalol after direct current cardioversion of chronic atrial fibrillation (part 5)

In the primary efficacy assessment, 15 of 24 patients (63%) treated with disopyramide, 13 of 22 (59%) with propafenone and 14 of 23 (61%) with sotalol were in sinus rhythm and on antiarrhythmic treatment at the six-month follow-up (not significant). … Continue reading

Comparison of disopyramide, propafenone and sotalol after direct current cardioversion of chronic atrial fibrillation (part 4)

Statistical analysis: Quantitative variables are given as mean ± SD. Quantitative variables were compared with Student’s t test for grouped data. The relation between qualitative variables was evaluated by the %2 law. P<0.05 was considered significant. RESULTS Sinus rhythm was … Continue reading

Comparison of disopyramide, propafenone and sotalol after direct current cardioversion of chronic atrial fibrillation (part 3)

Antiarrhythmic drugs administered before inclusion in the study were discontinued five half-lives before cardioversion. DC cardioversion was started on a low energy level of 2 J/kg body weight and, if necessary repeated on full energy (350 J). Randomization to antiarrhythmic … Continue reading

Comparison of disopyramide, propafenone and sotalol after direct current cardioversion of chronic atrial fibrillation (part 2)

PATIENTS AND METHODS Study patients: Between January 1991 and December 1994, patients referred from the out-patient clinic of the Central Clinical Hospital Medical Academy of Warsaw, Poland were evaluated for enrollment in this study. Entry criteria were age greater than … Continue reading

Comparison of disopyramide, propafenone and sotalol after direct current cardioversion of chronic atrial fibrillation (part 1)

Atrial fibrillation (AF) is a common sustained cardiac arrhythmia in clinical practice, and is responsible for considerable morbidity . The major adverse clinical consequences of AF are palpitations, impaired cardiac function, dyspnea, fatigue or syncope, and thromboembolism.

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